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2016;139(Suppl 1):21631

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During clinical trials, the mean time to maximum concentration (T max ) in plasma was 1 to 6 hours and varied across the dosing range

115 Exendin-3 (9-39) also blocks leptin-induced inhibition of food intake, and GLP-1 neurons in the NTS co-express leptin receptors, suggesting that the GLP-1 pathway may be one of the mediators of the anorectic effects of leptin